AN ARGININE-RICH MOTIF IN THE ORF2 CAPSID PROTEIN REGULATES THE HEPATITIS E VIRUS LIFECYCLE AND INTERACTIONS WITH THE HOST CELL.

Hepatitis E virus (HEV) infection is the most common cause of acute viral hepatitis worldwide.Hepatitis E is usually asymptomatic and self-limiting but it can become chronic in immunocompromised patients and is associated with increased fulminant hepatic failure and mortality rates in pregnant women.HEV genome encodes three proteins including the O

Objective: Multiple myeloma (MM) associated with extramedullary (EM) plasmacytoma has a poor therapeutic response and poor outcomes when treated with conventional chemotherapy.EM plasmacytoma is divided into two groups: the first group comprises tumors that are extending directly from osteolytic bone lesions (EM-B, bone-related), while the second r